Large volume leukapheresis for peripheral blood stem cell collection in children under 10 kg in weight
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چکیده
منابع مشابه
Management of anticoagulation-associated toxicity during large-volume leukapheresis of peripheral blood stem cell donors.
Management of anticoagulation-associated toxicity during large-volume leukapheresis of peripheral blood stem cell donors We write to direct attention to the management of anticoagulation-associated toxicity during large-volume leukapheresis (LVL), a potential source of donor morbidity as described in a recent comprehensive report comparing experiences during marrow and peripheral blood stem cel...
متن کاملFactors affecting autologous peripheral blood hematopoietic stem cell collections by large-volume leukapheresis: a single center experience.
OBJECTIVE To evaluate factors affecting peripheral blood hematopoietic stem cell yield in patients undergoing large-volume leukapheresis for autologous peripheral blood stem cell collection. METHODS Data from 304 consecutive autologous peripheral blood stem cell donors mobilized with hematopoietic growth factor (usually G-CSF), associated or not with chemotherapy, at Hospital Israelita Albert...
متن کاملAdvances in Hematopoietic Stem Cell Mobilization and Peripheral Blood Stem Cell Transplantation
Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...
متن کاملLarge-volume leukapheresis in pediatric patients: pre-apheresis peripheral blood CD34+ cell count predicts progenitor cell yield.
BACKGROUND AND OBJECTIVE In children it is very important to optimize PBPC harvesting and to reduce the number of leukaphereses per patient. The value of pre-apheresis peripheral blood CD34+ cell concentration as a predictor of PBPC yield was studied in 23 pediatric patients with hematologic and non-hematologic malignancies in order to optimize duration of PBPC collection. DESIGN AND METHODS ...
متن کاملCollection and transplantation of peripheral blood stem cells in very small children weighting 20 kg or less.
The safety and efficacy of harvesting peripheral blood hematopoietic stem cells (PBSC) were evaluated in 38 children weighing 20 kg or less, with the smallest patient weighing 7 kg. The patients had a median age of 42 months and included 26 children with acute leukemias or lymphoma and 12 with various solid tumors. A total of 81 aphereses were performed, mostly in the recovery phase of chemothe...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2003
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1703907